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TMEM59 antibody
TMEM59
Reactivity: Human
WB, ELISA, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TMEM59 Antibody
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Target
See all TMEM59 Antibodies
TMEM59
(Transmembrane Protein 59 (TMEM59))
Reactivity
All reactivities for TMEM59 antibodies
Human
Host
All hosts for TMEM59 antibodies
Rabbit
Clonality
All clonalities for TMEM59 antibodies
Polyclonal
Conjugate
All conjugates for TMEM59 antibodies
This TMEM59 antibody is un-conjugated
Application
All applications for TMEM59 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
transmembrane protein 59
Isotype
IgG
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Discover our top product TMEM59 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for TMEM59
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Target
TMEM59
(Transmembrane Protein 59 (TMEM59))
Alternative Name
TMEM59 (TMEM59 Products )
Synonyms
Tmem59 antibody, C1orf8 antibody, HSPC001 antibody, 1110001M20Rik antibody, 3110046P06Rik antibody, AI256529 antibody, D4Ertd20e antibody, MTDCF1 antibody, ORF18 antibody, transmembrane protein 59 antibody, tmem59 antibody, Tmem59 antibody, TMEM59 antibody
Background
Synonyms:C1orf8 Background:Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3(MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding.
Molecular Weight
41 kDa
Gene ID
9528
UniProt
Q9BXS4
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