UCHL1 antibody (AA 1-220)

Catalog No. ABIN7120476

The Rabbit Polyclonal anti-UCHL1 antibody (ABIN7120476) specifically detects UCHL1 in WB, IHC, ELISA and IP. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for UCHL1 antibody (AA 1-220) (ABIN7120476)

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UCHL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Product Details anti-UCHL1 Antibody

Binding Specificity: AA 1-220

Purpose: UCHL1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-220aa

Immunogen: ubiquitin carboxyl-terminal esterase L1(ubiquitin thiolesterase)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IHC:1:100-1:500, IP: 1:1000-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for UCHL1

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Alternative Name: UCHL1

Background:

Synonyms: Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)|Neuron cytoplasmic protein 9.5|PGP 9.5 (PGP9.5)|Ubiquitin thioesterase L1|UCHL1

Background: UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons(PMID: 6343558). This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm(PMID:7217993). And UCHL1 is a Parkinson's disease susceptibility gene(PMID:15048890).

Molecular Weight: 26 kDa

Gene ID: 7345

UniProt: P09936

Pathways: Feeding Behaviour