ZYX antibody

Catalog No. ABIN7121092

This Mouse Monoclonal antibody specifically detects ZYX in WB, IHC, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for ZYX antibody (ABIN7121092)

Target: ZYX (Zyxin (ZYX))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZYX antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: 8D5

Product Details anti-ZYX Antibody

Purpose: ZYX antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: zyxin

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ZYX

Target: ZYX (Zyxin (ZYX))

Alternative Name: ZYX

Background:

Synonyms: Zyxin|Zyxin-2|ZYX

Background: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin(ZYX) is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.

Molecular Weight: 80 kDa

Gene ID: 7791

UniProt: Q15942