CKB antibody

Catalog No. ABIN7126220

This Mouse Monoclonal antibody specifically detects CKB in PC. It exhibits reactivity toward Human.

Quick Overview for CKB antibody (ABIN7126220)

Target: CKB (Creatine Kinase, Brain (CKB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CKB antibody is un-conjugated

Application: Positive Control (PC)

Product Details anti-CKB Antibody

Specificity: Creatine kinases (CK) are a large family of isoenzymes that regulate levels of ATP in subcellular compartments, where they provide ATP at sites of fluctuating energy demand by the transfer of phosphates between creatine and adenine nucleotides. CKs provide the energy of phosphate hydrolysis necessary to drive the normal function of many cellular systems. In cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are three different isoenzymes: CKMM, CKBB and CKMB. This MAb recognizes the CKBB isoenzyme and does not react with the B subunit in CKMB.

Cross-Reactivity (Details): Human. Others-not tested.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human full-length CKBprotein

Isotype: IgG2b

Application Details

Application Notes:

Known_Application: Optimal dilution for a specific application should be determined.

Positive_Control: SH-SY5Y, HEK-293 and Cerebellum

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for CKB

Target: CKB (Creatine Kinase, Brain (CKB))

Alternative Name: CKB

Background: BCK, Brain creatine kinase, Ckb, Creatine kinase B chain, Creatine kinase B-type, Creatine Kinase BB Isoenzyme, Creatine phosphokinase BB, Epididymis luminal protein 211, Epididymis secretory protein Li 29, HEL 211,Creatine Phosphokinase-BB (CK-BB)
Cellular localisation: Cytoplasm

Molecular Weight: 42kDa

Gene ID: 1152, 173724

UniProt: P12277