Recombinant HIST1H2AB antibody (acLys9)

Catalog No. ABIN7127265

Product Details anti-HIST1H2AB Antibody

Target: HIST1H2AB (Histone Cluster 1, H2ab (HIST1H2AB))

Antibody Type: Recombinant Antibody

Binding Specificity: acLys9

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HIST1H2AB antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: Affinity-chromatography

Immunogen: A synthesized peptide

Clone: 3H5

Isotype: IgG

Application Details

Application Notes: Recommended dilution: ICC:1:50-1:500, IF:1:30-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HIST1H2AB

Target: HIST1H2AB (Histone Cluster 1, H2ab (HIST1H2AB))

Alternative Name: HIST1H2AB (HIST1H2AB Products)

Synonyms: H2A/m antibody, H2AFM antibody, H2A.1 antibody, H2a-53 antibody, histone cluster 1 H2A family member b antibody, histone cluster 1, H2ab antibody, HIST1H2AB antibody, Hist1h2ab antibody

Background:

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Aliases: Histone H2A type 1-B/E, Histone H2A.2, Histone H2A/a, Histone H2A/m, HIST1H2AB, H2AFM, AND, HIST1H2AE, H2AFA

UniProt: P04908

Pathways: Telomere Maintenance