Recombinant TINF2 antibody
Quick Overview for Recombinant TINF2 antibody (ABIN7127845)
Target
See all TINF2 (TIN2) AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Cross-Reactivity
- Human, Mouse, Rat
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Purification
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human Tin2
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Isotype
- IgG
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Application Notes
- Recommended dilution: WB:1:500-1:5000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
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Alternative Name
- TINF2
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Background
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Background: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.
Aliases: TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2), TINF2, TIN2
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UniProt
- Q9BSI4
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Pathways
- Cell Division Cycle, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process
Target
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