GADD45A antibody
Quick Overview for GADD45A antibody (ABIN7129566)
Target
See all GADD45A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- GADD45A Antibody
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Cross-Reactivity
- Mouse, Rat
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Purification
- Antigen affinity purification
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Immunogen
- Fusion protein of Human GADD45A
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
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Alternative Name
- GADD45A
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Background
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Background: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Aliases: DDIT 1 antibody, DDIT-1 antibody, DDIT1 antibody, DNA damage inducible transcript 1 antibody, DNA damage-inducible transcript 1 protein antibody, GA45A_HUMAN antibody, GADD45 antibody, GADD45A antibody, Growth arrest and DNA damage inducible 45 alpha antibody, Growth arrest and DNA damage inducible alpha antibody, Growth arrest and DNA damage-inducible protein GADD45 alpha antibody
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UniProt
- P24522
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Pathways
- p53 Signaling, Cell Division Cycle
Target
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