IKZF3 antibody

Catalog No. ABIN7129834

Product Details anti-IKZF3 Antibody

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKZF3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human IKZF3

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:5000, IHC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IKZF3

Target: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Alternative Name: IKZF3 (IKZF3 Products)

Synonyms: AIO antibody, AIOLOS antibody, ZNFN1A3 antibody, aio antibody, aiolos antibody, znfn1a3 antibody, IKZF3 antibody, 5830411O07Rik antibody, Aiolos antibody, Zfpn1a3 antibody, Znfn1a3 antibody, IKAROS family zinc finger 3 antibody, IKAROS family zinc finger 3 L homeolog antibody, IKZF3 antibody, ikzf3.L antibody, Ikzf3 antibody

Background:

Background: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

Aliases: AIO antibody, Aiolos antibody, IKAROS family zinc finger 3 (Aiolos) antibody, IKAROS family zinc finger 3 antibody, Ikaros family zinc finger protein 3 antibody, IKZF 3 antibody, IKZF3 antibody, IKZF3_HUMAN antibody, zinc finger DNA binding protein Aiolos antibody, Zinc finger protein Aiolos antibody, Zinc finger protein subfamily 1A 3 (Aiolos) antibody, Zinc finger protein subfamily 1A 3 antibody, Zinc finger protein subfamily 1A, member 3 antibody, ZNFN1A3 antibody

UniProt: Q9UKT9