OPTN antibody

Catalog No. ABIN7130502

Product Details anti-OPTN Antibody

Target: OPTN (Optineurin (OPTN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPTN antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human OPTN

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for OPTN

Target: OPTN (Optineurin (OPTN))

Alternative Name: OPTN (OPTN Products)

Synonyms: nrp antibody, fip2 antibody, hip7 antibody, hypl antibody, glc1e antibody, tfiiia-intp antibody, ALS12 antibody, FIP2 antibody, GLC1E antibody, HIP7 antibody, HYPL antibody, NRP antibody, TFIIIA-INTP antibody, Fip2 antibody, 4930441O07Rik antibody, fj52f04 antibody, si:ch211-240l19.3 antibody, wu:fj52f04 antibody, zgc:66386 antibody, zgc:77868 antibody, optineurin antibody, optineurin L homeolog antibody, OPTN antibody, optn antibody, Optn antibody, optn.L antibody

Background:

Background: This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.

Aliases: 14.7K interacting protein antibody, Ag9 C5 antibody, ALS12 antibody, E3 14.7K interacting protein antibody, E3-14.7K-interacting protein antibody, FIP 2 antibody, FIP-2 antibody, FIP2 antibody, Glaucoma 1 open angle E (adult onset) antibody, Glaucoma 1 open angle E antibody, GLC1E antibody, HIP 7 antibody, HIP-7 antibody, HIP7 antibody, Huntingtin interacting protein 7 antibody, Huntingtin interacting protein HYPL antibody, Huntingtin interacting protein L antibody, Huntingtin yeast partner L antibody, Huntingtin-interacting protein 7 antibody, Huntingtin-interacting protein L antibody, HYPL antibody, Injury inducible protein I 55 antibody, NEMO related protein antibody, NEMO-related protein antibody, NRP antibody, Optic neuropathy inducing protein antibody, Optic neuropathy-inducing protein antibody, Optineurin antibody, OPTN antibody, OPTN_HUMAN antibody, TFIIIA IntP antibody, TFIIIA-IntP antibody, Transcription factor IIIA interacting protein antibody, Transcription factor IIIA-interacting protein antibody, Tumor necrosis factor alpha inducible cellular protein containing leucine zipper domains antibody

UniProt: Q96CV9

Pathways: M Phase