PSMD3 antibody

Catalog No. ABIN7130740

This anti-PSMD3 antibody is a Rabbit Polyclonal antibody detecting PSMD3 in WB, IHC and ELISA. Suitable for Human.

Quick Overview for PSMD3 antibody (ABIN7130740)

Target: PSMD3 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 3 (PSMD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PSMD3 Antibody

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human PSMD3

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PSMD3

Target: PSMD3 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 3 (PSMD3))

Alternative Name: PSMD3

Background:

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count.

Aliases: 26S proteasome non ATPase regulatory subunit 3 antibody, 26S proteasome non-ATPase regulatory subunit 3 antibody, 26S proteasome regulatory subunit RPN3 antibody, 26S proteasome regulatory subunit S3 antibody, OTTHUMP00000164347 antibody, P58 antibody, Proteasome (prosome, macropain) 26S subunit non ATPase 3 antibody, Proteasome subunit p58 antibody, PSMD3 antibody, PSMD3_HUMAN antibody, RPN3 antibody, S3 antibody, Tissue specific transplantation antigen 2 antibody, TSTA2 antibody

UniProt: O43242

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway