SOCS6 antibody

Catalog No. ABIN7131139

The Rabbit Polyclonal anti-SOCS6 antibody (ABIN7131139) specifically detects SOCS6 in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for SOCS6 antibody (ABIN7131139)

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-SOCS6 Antibody

Purpose: SOCS6 Antibody

Cross-Reactivity: Mouse

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human SOCS6

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SOCS6

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Alternative Name: SOCS6

Background:

Background: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

Aliases: CIS-4 antibody, CIS4 antibody, Cish4 antibody, Cytokine inducible SH2 protein 4 antibody, Cytokine-inducible SH2 protein 4 antibody, HSPC060 antibody, SOCS-4 antibody, SOCS-6 antibody, SOCS4 antibody, Socs6 antibody, SOCS6_HUMAN antibody, SSI4 antibody, STAI4 antibody, STAT induced STAT inhibitor 4 antibody, STAT4 antibody, STATI4 antibody, Suppressor of cytokine signaling 4 antibody, Suppressor of cytokine signaling 6 antibody

UniProt: O14544

Pathways: JAK-STAT Signaling, Carbohydrate Homeostasis