Actin antibody (FITC)

Catalog No. ABIN7137910

This anti-Actin antibody is a Rabbit Polyclonal antibody detecting Actin in . Suitable for Mouse.

Quick Overview for Actin antibody (FITC) (ABIN7137910)

Target: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Actin antibody is conjugated to FITC

Application: Please inquire

Product Details anti-Actin Antibody (FITC)

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Mouse Actin, alpha skeletal muscle (Native Protein)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Actin

Target: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Alternative Name: Acta1

Background:

Background: Actin is a globular, roughly 42- kDa moonlighting protein found in all eukaryotic cells (the only known exception being nematode sperm) where it may be present at concentrations of over 100 μM. It is also one of the most highly-conserved proteins, differing by no more than 20 % in species as diverse as algae and humans. Actin is the monomeric subunit of two types of filaments in cells: microfilaments, one of the three major components of the cytoskeleton, and thin filaments, part of the contractile apparatus in muscle cells. Thus, actin participates in many important cellular processes including muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape. Many of these processes are mediated by extensive and intimate interactions of actin with cellular membranes. In vertebrates, three main groups of actin isoforms, alpha, beta, and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility.

Aliases: Acta1 antibody, ActaActin antibody, alpha skeletal muscle antibody, Alpha-actin-1) [Cleaved into: Actin antibody, alpha skeletal muscle antibody, intermediate form] antibody

UniProt: P68134

Pathways: Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development