YBX1 antibody (pSer102)

Catalog No. ABIN7138404

Product Details anti-YBX1 Antibody

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Binding Specificity: pSer102

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YBX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 102(L-R-S(p)-V-G) derived from Human YB1.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for YBX1

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Alternative Name: YBX1 (YBX1 Products)

Synonyms: BP-8 antibody, CSDA2 antibody, CSDB antibody, DBPB antibody, MDR-NF1 antibody, NSEP-1 antibody, NSEP1 antibody, YB-1 antibody, YB1 antibody, Byb1 antibody, Cbfa antibody, Dbpb antibody, Ef1a antibody, Msy1 antibody, Nsep1 antibody, Yb1 antibody, bp-8 antibody, csda2 antibody, csdb antibody, dbpb antibody, frgy1 antibody, mdr-nf1 antibody, nsep-1 antibody, nsep1 antibody, yb1 antibody, 1700102N10Rik antibody, C79409 antibody, EF1A antibody, MSY1 antibody, dbpB antibody, mYB-1a antibody, nuclease sensitive element binding protein 1 antibody, Y-box binding protein 1 antibody, Y box binding protein 1 antibody, Y-box binding protein 1 S homeolog antibody, nuclease-sensitive element-binding protein 1 antibody, Y box protein 1 antibody, nsep1 antibody, YBX1 antibody, Ybx1 antibody, ybx1.S antibody, LOC479011 antibody

Background:

Background:

YB-1 is a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs). Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A)n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP.

Sakura H., Gene 73:499-507(1988).
Didier D.K. Proc. Natl. Acad. Sci. U.S.A. 85:7322-7326(1988).
Kolluri R., Nucleic Acids Res. 19:4771-4771(1991).

Aliases: BP 8 antibody, CBF-A antibody, CCAAT binding transcription factor I subunit A antibody, CCAAT-binding transcription factor I subunit A antibody, CSDA2 antibody, CSDB antibody, DBPB antibody, DNA binding protein B antibody, DNA-binding protein B antibody, EFI-A antibody, Enhancer factor I subunit A antibody, MDR NF1 antibody, MGC104858 antibody, MGC110976 antibody, MGC117250 antibody, NSEP 1 antibody, NSEP1 antibody, Nuclease sensitive element binding protein 1 antibody, Nuclease-sensitive element-binding protein 1 antibody, p50 antibody, Q15905 antibody, Y-box binding protein 1 antibody, Y-box transcription factor antibody, Y-box-binding protein 1 antibody, YB 1 antibody, YB-1 antibody, YBOX1_HUMAN antibody, YBX 1 antibody, ybx1 antibody

UniProt: P67809

Pathways: Regulation of Muscle Cell Differentiation