BRAF antibody (pSer446)

Catalog No. ABIN7138622

This Rabbit Polyclonal antibody specifically detects BRAF in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for BRAF antibody (pSer446) (ABIN7138622)

Target: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRAF antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BRAF Antibody

Binding Specificity: pSer446

Cross-Reactivity: Human, Mouse

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 446(R-D-S(p)-S-D) derived from Human B-RAF.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BRAF

Target: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Alternative Name: BRAF

Background:

Background: Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron.

Aliases: FLJ95109 antibody, 94 kDa B raf protein antibody, B raf 1 antibody, B raf antibody, B Raf proto oncogene serine threonine protein kinase antibody, B Raf proto oncogene, serine/threonine kinase antibody, B RAF1 antibody, B-Raf proto-oncogene serine/threonine-protein kinase (p94) antibody, BRAF 1 antibody, BRAF antibody, BRAF_HUMAN antibody, BRAF1 antibody, cRmil antibody, MGC126806 antibody, MGC138284 antibody, Murine sarcoma viral (v-raf) oncogene homolog B1 antibody, Murine sarcoma viral v raf oncogene homolog B1 antibody, NS7 antibody, Oncogen BRAF antibody, oncogene BRAF1 antibody, p94 antibody, Proto-oncogene B-Raf antibody, Proto-oncogene c-Rmil antibody, RAFB 1 antibody, RAFB1 antibody, RMIL antibody, Serine/threonine-protein kinase B-raf antibody, v raf murine sarcoma viral oncogene homolog B antibody, v raf murine sarcoma viral oncogene homolog B1 antibody, v-Raf murine sarcoma viral oncogene homolog B1 antibody

UniProt: P15056

Pathways: MAPK Signaling, RTK Signaling, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy