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MDC1 antibody (pSer513)

MDC1 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7138640
  • Target See all MDC1 Antibodies
    MDC1 (Mdc1 (MDC1))
    Binding Specificity
    • 22
    • 16
    • 15
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer513
    Reactivity
    • 59
    • 54
    • 16
    • 12
    • 11
    • 2
    • 1
    • 1
    Human
    Host
    • 49
    • 37
    Rabbit
    Clonality
    • 49
    • 37
    Polyclonal
    Conjugate
    • 29
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MDC1 antibody is un-conjugated
    Application
    • 67
    • 31
    • 13
    • 13
    • 13
    • 13
    • 11
    • 10
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Human
    Purification
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    Immunogen
    Peptide sequence around phosphorylation site of Serine 513(E-R-S(p)-Q-A) derived from Human MDC1.
    Isotype
    IgG
    Top Product
    Discover our top product MDC1 Primary Antibody
  • Application Notes
    IHC:1:50-1:100,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MDC1 (Mdc1 (MDC1))
    Alternative Name
    MDC1 (MDC1 Products)
    Synonyms
    6820401C03 antibody, AA413496 antibody, Nfbd1 antibody, mKIAA0170 antibody, NFBD1 antibody, mediator of DNA damage checkpoint 1 antibody, mediator of DNA-damage checkpoint 1 antibody, Mdc1 antibody, MDC1 antibody
    Background

    Background:

    The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint.

    Nagase T., DNA Res. 3:17-24(1996).
    Shiina T., Genetics 173:1555-1570(2006).
    Mungall A.J., Nature 425:805-811(2003).

    Aliases: Homologue to Drosophila photoreceptor protein calphotin antibody, MDC 1 antibody, Mdc1 antibody, MDC1_HUMAN antibody, Mediation of DNA damage checkpoint 1 antibody, Mediator of DNA damage checkpoint 1 antibody, Mediator of DNA damage checkpoint protein 1 antibody, NFBD 1 antibody, NFBD1 antibody, Nuclear factor with BRCT domains 1 antibody, Nuclear Factor with BRCT Domains Protein 1 antibody

    UniProt
    Q14676
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