STAT5A antibody (pTyr694)

Catalog No. ABIN7139047

The Rabbit Polyclonal anti-STAT5A antibody (ABIN7139047) specifically detects STAT5A in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for STAT5A antibody (pTyr694) (ABIN7139047)

Target: STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT5A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-STAT5A Antibody

Binding Specificity: pTyr694

Purpose: Phospho-STAT5A (Tyr694) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 694 (D-G-Y(p)-V-K) derived from Human STAT5A.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for STAT5A

Target: STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))

Alternative Name: STAT5A

Background:

Background: Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.

Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369.
Dentelli P, et al. (1999) J Immunol. 163: 2151-2159.
Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.

Aliases: MGF antibody, Signal transducer and activator of transcription 5A antibody, Signal Transducer and Activator of Transcription 5B antibody, STA5A_HUMAN antibody, STAT 5A antibody, STAT 5B antibody, STAT5 antibody, STAT5A antibody, STAT5B antibody, Transcription factor STAT5A antibody, Transcription factor STAT5B antibody

UniProt: P42229

Pathways: JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation