MICAL2 antibody (AA 1-495) (HRP)
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- Target See all MICAL2 Antibodies
- MICAL2 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2))
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Binding Specificity
- AA 1-495
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MICAL2 antibody is conjugated to HRP
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human [F-actin]-monooxygenase MICAL2 protein (1-495AA)
- Isotype
- IgG
- Top Product
- Discover our top product MICAL2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- MICAL2 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2))
- Alternative Name
- MICAL2 (MICAL2 Products)
- Synonyms
- MICAL-2 antibody, MICAL2PV1 antibody, MICAL2PV2 antibody, 5330438E18Rik antibody, 9530064J02 antibody, mKIAA0750 antibody, RGD1311773 antibody, microtubule associated monooxygenase, calponin and LIM domain containing 2 antibody, MICAL2 antibody, Mical2 antibody
- Background
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Background: Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin and regulates the SRF signaling. Acts by modifying nuclear actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization. Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA.
Aliases: MICAL2 antibody, KIAA0750 antibody, MICAL2PV1 antibody, MICAL2PV2 antibody, [F-actin]-monooxygenase MICAL2 antibody, EC 1.14.13.225 antibody, Molecule interacting with CasL protein 2 antibody, MICAL-2 antibody
- UniProt
- O94851
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