DPH1 antibody (AA 192-318) (Biotin)
Quick Overview for DPH1 antibody (AA 192-318) (Biotin) (ABIN7142123)
Target
See all DPH1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 192-318
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 protein (192-318AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DPH1 (DPH1 Homolog (DPH1))
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Alternative Name
- DPH1
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Background
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Background: Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2). When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells. Acts also as a tumor suppressor in lung and breast cancers (By similarity). Plays a role in embryonic growth, organogenesis and postnatal survival.
Aliases: Candidate tumor suppressor in ovarian cancer 1 antibody, Diphthamide biosynthesis protein 1 antibody, Diphthamide biosynthesis protein 2 homolog like 1 antibody, Diphthamide biosynthesis protein 2 homolog-like 1 antibody, Diphthamide biosynthesis protein 2 like antibody, Diphthamide biosynthesis protein 2-like antibody, Diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces) like 1 antibody, Diptheria toxin resistance protein required for diphthamide biosynthesis like 1 antibody, DPH like 1 (S. cerevisiae) antibody, DPH like 1 antibody, DPH-like 1 antibody, DPH1 antibody, DPH1 homolog (S. cerevisiae) antibody, DPH1 homolog antibody, DPH1_HUMAN antibody, DPH2 like 1 antibody, DPH2-like 1 antibody, DPH2L antibody, DPH2L1 antibody, FLJ33211 antibody, HsDph1 antibody, Ovarian cancer associated gene 1 antibody, Ovarian cancer associated gene 1 protein antibody, Ovarian cancer-associated gene 1 protein antibody, Ovarian tumor suppressor candidate 1 antibody
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UniProt
- Q9BZG8
Target
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