PSMD5 antibody (Regulatory Subunit 5)

Catalog No. ABIN7142216

Product Details anti-PSMD5 Antibody

Target: PSMD5 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 5 (PSMD5))

Binding Specificity: AA 255-504, Regulatory Subunit 5

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD5 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human 26S proteasome non-ATPase regulatory subunit 5 protein (255-504AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PSMD5

Target: PSMD5 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 5 (PSMD5))

Alternative Name: PSMD5 (PSMD5 Products)

Synonyms: S5B antibody, 1500032A03Rik antibody, AW475925 antibody, S5b antibody, W91691 antibody, mKIAA0072 antibody, proteasome 26S subunit, non-ATPase 5 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 antibody, PSMD5 antibody, Psmd5 antibody

Background:

Background: Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5.

Aliases: 26S protease subunit S5 basic antibody, 26S proteasome non-ATPase regulatory subunit 5 antibody, 26S proteasome subunit S5B antibody, Protease 26S, subunit 5B antibody, Proteasome (prosome, macropain) 26S subunit, non ATPase, 5 antibody, Proteasome 19S S5B antibody, Proteasome 26S subunit, non ATPase, 5 antibody, PSMD5 antibody, PSMD5_HUMAN antibody, S5B antibody

UniProt: Q16401

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway