ARAP3 antibody (AA 163-320) (Biotin)

Catalog No. ABIN7144569

Product Details anti-ARAP3 Antibody (Biotin)

Target: ARAP3 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 3 (ARAP3))

Binding Specificity: AA 163-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARAP3 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 protein (163-320AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ARAP3

Target: ARAP3 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 3 (ARAP3))

Alternative Name: ARAP3 (ARAP3 Products)

Synonyms: CENTD3 antibody, ARAP3 antibody, Arap3-ps1 antibody, Centd3 antibody, RGD1304938 antibody, DRAG1 antibody, Drag1 antibody, E030006K04Rik antibody, cnt-d3 antibody, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 antibody, ARAP3 antibody, arap3 antibody, Arap3 antibody

Background:

Background: Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.

Aliases: ARAP3 antibody, CENTD3 antibody, Arf-GAP with Rho-GAP domain antibody, ANK repeat and PH domain-containing protein 3 antibody, Centaurin-delta-3 antibody, Cnt-d3 antibody

UniProt: Q8WWN8