ATP5F1A (AA 44-553) antibody (Biotin)

Catalog No. ABIN7343925

Product Details

Target: ATP5F1A

Binding Specificity: AA 44-553

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human ATP synthase subunit alpha, mitochondrial protein (44-553AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: ATP5F1A

Background:

Background: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F1. Rotation of the central stalk against the surrounding alpha3beta3 subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites.

Aliases: ATP synthase alpha chain antibody, ATP synthase alpha chain, mitochondrial antibody, ATP synthase subunit alpha antibody, ATP synthase subunit alpha mitochondrial antibody, ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle antibody, ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, 1 antibody, ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle antibody, ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 2, non-cardiac muscle-like 2 antibody, ATP sythase (F1 ATPase) alpha subunit antibody, ATP5A antibody, Atp5a1 antibody, ATP5AL2 antibody, ATPA_HUMAN antibody, ATPM antibody, Epididymis secretory sperm binding protein Li 123m antibody, hATP1 antibody, HEL-S-123m antibody, MC5DN4 antibody, mitochondrial antibody, Mitochondrial ATP synthetase antibody, Mitochondrial ATP synthetase oligomycin resistant antibody, Modifier of Min 2 antibody, Modifier of Min 2 mouse homolog antibody, Modifier of Min 2, mouse, homolog of antibody, MOM2 antibody, OMR antibody, ORM antibody, OTTHUMP00000163475 antibody

UniProt: P25705