CDCA8 antibody (AA 1-280)
Quick Overview for CDCA8 antibody (AA 1-280) (ABIN7145712)
Target
See all CDCA8 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-280
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Borealin protein (1-280AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CDCA8 (Cell Division Cycle Associated 8 (CDCA8))
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Alternative Name
- CDCA8
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Background
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Background: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.
Aliases: BOR antibody, BOREA_HUMAN antibody, Borealin antibody, CDCA8 antibody, Cell division cycle associated 8 antibody, cell division cycle associated protein 8 antibody, Cell division cycle-associated protein 8 antibody, Dasra B antibody, Dasra-B antibody, DasraB antibody, FLJ10468 antibody, FLJ12042 antibody, hDasra B antibody, hDasra-B antibody, MESRGP antibody, OTTHUMP00000004514 antibody, pluripotent embryonic stem cell related gene 3 protein antibody, Pluripotent embryonic stem cell-related gene 3 protein antibody
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UniProt
- Q53HL2
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Pathways
- Cell Division Cycle, M Phase
Target
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