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E-cadherin antibody (AA 155-707)

This Mouse Monoclonal antibody specifically detects E-cadherin in WB, FACS, IF and ELISA. It exhibits reactivity toward Human.
Catalog No. ABIN7146194

Quick Overview for E-cadherin antibody (AA 155-707) (ABIN7146194)

Target

See all E-cadherin (CDH1) Antibodies
E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Reactivity

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Human

Host

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  • 106
  • 6
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  • 2
Mouse

Clonality

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  • 143
  • 5
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Monoclonal

Conjugate

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  • 32
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  • 1
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This E-cadherin antibody is un-conjugated

Application

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA

Clone

9H2D3
  • Binding Specificity

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    AA 155-707

    Cross-Reactivity

    Human, Mouse

    Purification

    Protein G purified

    Immunogen

    Recombinant Human Cadherin-1 protein (155-707AA)

    Isotype

    IgG1, IgG1 kappa
  • Application Notes

    Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

    Alternative Name

    CDH1

    Background

    Background: Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.

    Aliases: Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1, E-Cad/CTF2, E-Cad/CTF3], CDH1, CDHE UVO

    UniProt

    P12830

    Pathways

    WNT Signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation
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