E-cadherin antibody (AA 155-707)
Quick Overview for E-cadherin antibody (AA 155-707) (ABIN7146194)
Target
See all E-cadherin (CDH1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 155-707
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Cross-Reactivity
- Human, Mouse
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Purification
- Protein G purified
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Immunogen
- Recombinant Human Cadherin-1 protein (155-707AA)
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Isotype
- IgG1, IgG1 kappa
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Application Notes
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
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Alternative Name
- CDH1
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Background
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Background: Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Aliases: Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1, E-Cad/CTF2, E-Cad/CTF3], CDH1, CDHE UVO
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UniProt
- P12830
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Pathways
- WNT Signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation
Target
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