CARD11 antibody (AA 985-1154)

Catalog No. ABIN7146906

The Rabbit Polyclonal anti-CARD11 antibody is suitable to detect CARD11 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for CARD11 antibody (AA 985-1154) (ABIN7146906)

Target: CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CARD11 Antibody

Binding Specificity: AA 985-1154

Purpose: CARD11 Antibody

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Caspase recruitment domain-containing protein 11 protein (985-1154AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CARD11

Target: CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Alternative Name: CARD11

Background:

Background: Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.

Aliases: 0610008L17Rik antibody, 2410011D02Rik antibody, Bcl10 interacting maguk protein 3 antibody, BIMP 3 antibody, BIMP3 antibody, CAR11_HUMAN antibody, CARD 11 antibody, CARD containing MAGUK protein 3 antibody, Card maguk protein 1 antibody, CARD-containing MAGUK protein 1 antibody, CARD11 antibody, CARD11 protein antibody, Carma 1 antibody, CARMA1 antibody, Caspase recruitment domain containing protein 11 antibody, Caspase recruitment domain family member 11 antibody, Caspase recruitment domain-containing protein 11 antibody, MGC133069 antibody

UniProt: Q9BXL7

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling