Integrin beta 2 antibody (AA 24-220)

Catalog No. ABIN7147132

This anti-Integrin beta 2 antibody is a Rabbit Polyclonal antibody detecting Integrin beta 2 in WB, IHC and ELISA. Suitable for Human.

Quick Overview for Integrin beta 2 antibody (AA 24-220) (ABIN7147132)

Target: Integrin beta 2 (ITGB2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Integrin beta 2 Antibody

Binding Specificity: AA 24-220

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human CD180 antigen protein (24-220AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: CD18

Background:

Background: May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity).

Aliases: CD180 antibody, CD180 antigen antibody, CD180_HUMAN antibody, F630107B15 antibody, LY64 antibody, Ly78 antibody, Lymphocyte antigen 64 antibody, lymphocyte antigen 64 radioprotective 105 kDa antibody, lymphocyte antigen-64, radioprotective, 105 kDa antibody, MGC126233 antibody, MGC126234 antibody, Radioprotective 105 kDa protein antibody, RP105 antibody

UniProt: Q99467

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation