CDK5RAP2 antibody (Regulatory Subunit) (Biotin)
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- Target See all CDK5RAP2 Antibodies
- CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))
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Binding Specificity
- AA 996-1111, Regulatory Subunit
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDK5RAP2 antibody is conjugated to Biotin
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human CDK5 regulatory subunit-associated protein 2 protein (996-1111AA)
- Isotype
- IgG
- Top Product
- Discover our top product CDK5RAP2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))
- Alternative Name
- CDK5RAP2 (CDK5RAP2 Products)
- Synonyms
- EGFL5 antibody, C48 antibody, Cep215 antibody, MCPH3 antibody, 2900018K03Rik antibody, an antibody, mKIAA1633 antibody, CDK5 regulatory subunit associated protein 2 antibody, CDK5 regulatory subunit-associated protein 2 antibody, CDK5RAP2 antibody, LOC100156240 antibody, cdk5rap2 antibody, Cdk5rap2 antibody
- Background
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Background: Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with MAPRE1, it may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends. Regulates centrosomal maturation by recruitment of a gamma-tubulin ring complex onto centrosomes (PubMed:26485573).
Aliases: C48 antibody, CDK5 activator-binding protein C48 antibody, CDK5 regulatory subunit associated protein 2 antibody, CDK5 regulatory subunit-associated protein 2 antibody, CDK5RAP2 antibody, centrosomal protein 215 kDa antibody, Centrosome-associated protein 215 antibody, CEP215 antibody, CK5P2_HUMAN antibody, MCPH3 antibody
- UniProt
- Q96SN8
- Pathways
- M Phase, SARS-CoV-2 Protein Interactome
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