CHAF1A antibody (AA 840-904)

Catalog No. ABIN7147681

Product Details anti-CHAF1A Antibody

Target: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Binding Specificity: AA 840-904

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHAF1A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Chromatin assembly factor 1 subunit A protein (840-904AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CHAF1A

Target: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Alternative Name: CHAF1A (CHAF1A Products)

Synonyms: CHAF1A antibody, CAF-1 antibody, CAF1 antibody, CAF1B antibody, CAF1P150 antibody, P150 antibody, AL023013 antibody, AL024058 antibody, Cac1p antibody, CAF-1P150 antibody, CAF-I-p150 antibody, CAF-Ip150 antibody, caip150 antibody, wu:fd14g10 antibody, zgc:153930 antibody, chaf1a-b antibody, xp150 antibody, chromatin assembly factor 1 subunit A antibody, chromatin assembly factor 1, subunit A (p150) antibody, chromatin assembly factor 1 subunit A S homeolog antibody, Chaf1a antibody, CHAF1A antibody, LOC100447657 antibody, chaf1a antibody, chaf1a.S antibody

Background:

Background: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity).

Aliases: CAF 1 antibody, CAF 1 subunit A antibody, CAF antibody, CAF I 150 kDa subunit antibody, CAF I p150 antibody, CAF-1 subunit A antibody, CAF-I 150 kDa subunit antibody, CAF-I p150 antibody, CAF1 antibody, CAF1A_HUMAN antibody, CAF1B antibody, CAF1P150 antibody, CHAF1A antibody, Chromatin assembly factor 1 subunit A antibody, Chromatin Assembly Factor 1 Subunit A p150 antibody, Chromatin assembly factor I (150 kDa) antibody, Chromatin assembly factor I 150 kDa antibody, Chromatin assembly factor I p150 subunit antibody, DCAF1 antibody, hp150 antibody, MGC71229 antibody, P150 antibody

UniProt: Q13111