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C4B antibody (AA 1454-1744) (HRP)

C4b Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7148368
  • Target See all C4B (C4b) Antibodies
    C4B (C4b) (Complement Component C4b (C4b))
    Binding Specificity
    • 15
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1454-1744
    Reactivity
    • 38
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 49
    • 5
    • 3
    Rabbit
    Clonality
    • 52
    • 5
    Polyclonal
    Conjugate
    • 20
    • 8
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C4B antibody is conjugated to HRP
    Application
    • 30
    • 23
    • 14
    • 13
    • 13
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Complement C4-B protein (1454-1744AA)
    Isotype
    IgG
    Top Product
    Discover our top product C4b Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    C4B (C4b) (Complement Component C4b (C4b))
    Alternative Name
    C4B (C4b Products)
    Synonyms
    C4B1 antibody, C4B12 antibody, C4B2 antibody, C4B3 antibody, C4B5 antibody, C4BD antibody, C4B_2 antibody, C4F antibody, CH antibody, CO4 antibody, CPAMD3 antibody, C4 antibody, C4A2 antibody, C4A3 antibody, C4A4 antibody, C4A6 antibody, C4AD antibody, C4S antibody, CPAMD2 antibody, RG antibody, wu:fi14a03 antibody, C4B antibody, DKFZP469I0332 antibody, Slp antibody, Ss antibody, C4-2 antibody, C4l antibody, complement C4B (Chido blood group) antibody, complement C4A (Rodgers blood group) antibody, complement component 4 antibody, complement C4-B antibody, complement component 4B (Chido blood group) antibody, complement component 4A (Rodgers blood group) antibody, C4B antibody, C4A antibody, c4 antibody, LOC462577 antibody, C4a antibody, C4b antibody
    Background

    Background: Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. Ref.16 Ref.17 Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

    Aliases: Basic complement C4 antibody, C2B5 antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 antibody, C4b antibody, C4B1 antibody, C4B2 antibody, C4B3 antibody, CO4B_HUMAN antibody, Complement C4 gamma chain antibody, Complement component 4B antibody, CPAMD3 antibody

    UniProt
    P0C0L5
    Pathways
    Complement System
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