CIR1 antibody (AA 1-160)
Quick Overview for CIR1 antibody (AA 1-160) (ABIN7148571)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-160
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Corepressor interacting with RBPJ 1 protein (1-160AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CIR1
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Background
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Background: May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription.
Aliases: CIR1 antibody, CIRCorepressor interacting with RBPJ 1 antibody, CBF1-interacting corepressor antibody, Recepin antibody
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UniProt
- Q86X95
Target
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