HSD11B1 antibody (AA 25-292) (Biotin)

Catalog No. ABIN7148613

The Rabbit Polyclonal anti-HSD11B1 antibody has been validated for ELISA. It is suitable to detect HSD11B1 in samples from Human.

Quick Overview for HSD11B1 antibody (AA 25-292) (Biotin) (ABIN7148613)

Target: HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD11B1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-HSD11B1 Antibody (Biotin)

Binding Specificity: AA 25-292

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Corticosteroid 11-beta-dehydrogenase isozyme 1 protein (25-292AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HSD11B1

Target: HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))

Alternative Name: HSD11B1

Background:

Background: Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol.

Aliases: 11 beta HSD 1 antibody, 11 beta HSD1 antibody, 11 beta hydroxysteroid dehydrogenase 1 antibody, 11 DH antibody, 11-beta hydroxysteroid dehydrogenase, type 1 antibody, 11-beta-HSD1 antibody, 11-beta-hydroxysteroid dehydrogenase 1 antibody, 11-DH antibody, 11DH antibody, Corticosteroid 11 beta dehydrogenase isozyme 1 antibody, Corticosteroid 11-beta-dehydrogenase isozyme 1 antibody, CORTRD2 antibody, DHI1_HUMAN antibody, HDL antibody, HSD 11 antibody, HSD11 antibody, HSD11B antibody, HSD11B1 antibody, HSD11L antibody, Hydroxysteroid (11 beta) dehydrogenase antibody, Hydroxysteroid (11 beta) dehydrogenase 1 antibody, MGC13539 antibody, SDR26C1 antibody, short chain dehydrogenase/reductase family 26C, member 1 antibody

UniProt: P28845

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process