MCM4 antibody (AA 2-141)

Catalog No. ABIN7150334

Product Details anti-MCM4 Antibody

Target: MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))

Binding Specificity: AA 2-141

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DNA replication licensing factor MCM4 protein (2-141AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MCM4

Target: MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))

Alternative Name: MCM4 (MCM4 Products)

Synonyms: cdc21 antibody, CDC21 antibody, CDC54 antibody, NKCD antibody, NKGCD antibody, P1-CDC21 antibody, hCdc21 antibody, 19G antibody, AI325074 antibody, AU045576 antibody, Cdc21 antibody, Mcmd4 antibody, mKIAA4003 antibody, mcdc21 antibody, cb1025 antibody, fc12c09 antibody, fj85g09 antibody, hm:zeh1616 antibody, wu:fc12c09 antibody, wu:fj85g09 antibody, zeh1616 antibody, minichromosome maintenance complex component 4 L homeolog antibody, minichromosome maintenance complex component 4 S homeolog antibody, minichromosome maintenance complex component 4 antibody, mcm4.L antibody, mcm4.S antibody, MCM4 antibody, mcm4 antibody, Mcm4 antibody

Background:

Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for \\\'once per cell cycle\\\' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.

Aliases: 19G antibody, AI325074 antibody, AU045576 antibody, CDC 21 antibody, CDC 54 antibody, CDC21 antibody, CDC21 homolog antibody, CDC21, S. pombe, homolog of antibody, CDC54 antibody, Cell division cycle 21, S. pombe, homolog of antibody, DNA replication licensing factor MCM 4 antibody, DNA replication licensing factor MCM4 antibody, hCdc 21 antibody, hCdc21 antibody, Homolog of S. pombe cell devision cycle 21 antibody, KIAA4003 antibody, mcdc21 antibody, MCM 4 antibody, MCM 4 minichromosome maintenance deficient 4 antibody, mcm4 antibody, MCM4 minichromosome maintenance deficient 4 antibody, MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) antibody, MCM4_HUMAN antibody, Mcmd4 antibody, MGC33310 antibody, Minichromosome maintenance 4 antibody, Minichromosome maintenance complex component 4 antibody, Minichromosome maintenance deficient (S. cerevisiae) 4 antibody, Minichromosome maintenance deficient 4 antibody, Minichromosome maintenance deficient 4 homolog (S. cerevisiae) antibody, Minichromosome maintenance, S. cerevisiae, homolog of, 4 antibody, mKIAA4003 antibody, NKCD antibody, NKGCD antibody, P1 CDC21 antibody, P1-CDC21 antibody, P1CDC21 antibody

UniProt: P33991

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA