RNF40 antibody (AA 471-724) (FITC)

Catalog No. ABIN7150993

The FITC-conjugated Rabbit Polyclonal anti-RNF40 antibody (ABIN7150993) specifically detects RNF40. The antibody is reactive with Human samples.

Quick Overview for RNF40 antibody (AA 471-724) (FITC) (ABIN7150993)

Target: RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF40 antibody is conjugated to FITC

Application: Please inquire

Product Details anti-RNF40 Antibody (FITC)

Binding Specificity: AA 471-724

Purpose: RNF40 Antibody, FITC conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human E3 ubiquitin-protein ligase BRE1B protein (471-724AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RNF40

Target: RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))

Alternative Name: RNF40

Background:

Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of \'Lys-120\' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 \'Lys-4\' and \'Lys-79\' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.

Aliases: 95 kDa retinoblastoma associated protein antibody, 95 kDa retinoblastoma protein binding protein antibody, 95 kDa retinoblastoma-associated protein antibody, BRE 1B antibody, BRE1 B antibody, BRE1 E3 ubiquitin ligase homolog B antibody, BRE1-B antibody, BRE1B antibody, BRE1B_HUMAN antibody, DKFZp686K191 antibody, E3 ubiquitin protein ligase BRE1B antibody, E3 ubiquitin-protein ligase BRE1B antibody, KIAA0661 antibody, MGC13051 antibody, Rb associated protein antibody, RBP 95 antibody, RBP95 antibody, RING finger protein 40 antibody, Ring finger protein 40 E3 ubiquitin protein ligase antibody, RNF 40 antibody, Rnf40 antibody, STARING antibody

UniProt: O75150