LRSAM1 antibody (AA 1-290)
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- Target See all LRSAM1 Antibodies
- LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))
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Binding Specificity
- AA 1-290
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LRSAM1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Cross-Reactivity
- Human, Mouse
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human E3 ubiquitin-protein ligase LRSAM1 protein (1-290AA)
- Isotype
- IgG
- Top Product
- Discover our top product LRSAM1 Primary Antibody
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- Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))
- Alternative Name
- LRSAM1 (LRSAM1 Products)
- Synonyms
- CMT2P antibody, RIFLE antibody, TAL antibody, leucine rich repeat and sterile alpha motif containing 1 antibody, LRSAM1 antibody, Lrsam1 antibody
- Background
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Background: E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos (PubMed:15256501). Bacterial recognition protein that defends the cytoplasm from invasive pathogens (PubMed:23245322). Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation (xenophagy) (PubMed:23245322, PubMed:25484098).
Aliases: CMT2P antibody, E3 ubiquitin protein ligase LRSAM1 antibody, E3 ubiquitin-protein ligase LRSAM1 antibody, EC 6.3.2.- antibody, FLJ31641 antibody, hTAL antibody, Leucine rich repeat and sterile alpha motif containing 1 antibody, Leucine rich repeat and sterile alpha motif containing protein 1 antibody, Leucine-rich repeat and sterile alpha motif-containing protein 1 antibody, LRSAM1 antibody, LRSM1_HUMAN antibody, OTTHUMP00000022174 antibody, OTTHUMP00000022175 antibody, RIFLE antibody, TAL antibody, Tsg101 associated ligase antibody, Tsg101-associated ligase antibody
- UniProt
- Q6UWE0
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