MIB2 antibody (AA 1-128)

Catalog No. ABIN7151067

The Rabbit Polyclonal anti-MIB2 antibody has been validated for IHC and ELISA. It is suitable to detect MIB2 in samples from Human.

Quick Overview for MIB2 antibody (AA 1-128) (ABIN7151067)

Target: MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIB2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-MIB2 Antibody

Binding Specificity: AA 1-128

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase MIB2 protein (1-128AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MIB2

Target: MIB2 (E3 ubiquitin-protein ligase MIB2 (MIB2))

Alternative Name: MIB2

Background:

Background: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.

Aliases: MIB2 antibody, SKD antibody, ZZANK1 antibody, E3 ubiquitin-protein ligase MIB2 antibody, EC 2.3.2.27 antibody, Mind bomb homolog 2 antibody, Novel zinc finger protein antibody, Novelzin antibody, Putative NF-kappa-B-activating protein 002N antibody, RING-type E3 ubiquitin transferase MIB2 antibody, Skeletrophin antibody, Zinc finger ZZ type with ankyrin repeat domain protein 1 antibody

UniProt: Q96AX9

Pathways: Notch Signaling