EIF4EBP3 antibody (AA 1-100) (Biotin)

Catalog No. ABIN7152206

Product Details anti-EIF4EBP3 Antibody (Biotin)

Target: EIF4EBP3 (Eukaryotic Translation Initiation Factor 4E Binding Protein 3 (EIF4EBP3))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4EBP3 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Eukaryotic translation initiation factor 4E-binding protein 3 protein (1-100AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EIF4EBP3

Target: EIF4EBP3 (Eukaryotic Translation Initiation Factor 4E Binding Protein 3 (EIF4EBP3))

Alternative Name: EIF4EBP3 (EIF4EBP3 Products)

Synonyms: zgc:103720 antibody, 4E-BP3 antibody, 4EBP3 antibody, 4e-bp3 antibody, eukaryotic translation initiation factor 4E binding protein 3 antibody, eif4ebp3 antibody, Eif4ebp3 antibody, EIF4EBP3 antibody

Background:

Background: Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.

Aliases: EIF4EBP3Eukaryotic translation initiation factor 4E-binding protein 3 antibody, 4E-BP3 antibody, eIF4E-binding protein 3 antibody

UniProt: O60516