FGF19 antibody (AA 25-216) (Biotin)
Quick Overview for FGF19 antibody (AA 25-216) (Biotin) (ABIN7152796)
Target
See all FGF19 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 25-216
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Fibroblast growth factor 19 protein (25-216aa)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FGF19 (Fibroblast Growth Factor 19 (FGF19))
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Alternative Name
- FGF19
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Background
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Background: Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
Aliases: Fibroblast growth factor 19 (FGF-19), FGF19
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UniProt
- O95750
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Target
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