GADD45A antibody (AA 1-165) (Biotin)

Catalog No. ABIN7154465

This Rabbit Polyclonal antibody specifically detects GADD45A in ELISA. It exhibits reactivity toward Human.

Quick Overview for GADD45A antibody (AA 1-165) (Biotin) (ABIN7154465)

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GADD45A antibody is conjugated to Biotin

Application: ELISA

Product Details anti-GADD45A Antibody (Biotin)

Binding Specificity: AA 1-165

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Growth arrest and DNA damage-inducible protein GADD45 alpha protein (1-165AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GADD45A

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Alternative Name: GADD45A

Background:

Background: In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes, stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.

Aliases: DDIT 1 antibody, DDIT-1 antibody, DDIT1 antibody, DNA damage inducible transcript 1 antibody, DNA damage-inducible transcript 1 protein antibody, GA45A_HUMAN antibody, GADD45 antibody, GADD45A antibody, Growth arrest and DNA damage inducible 45 alpha antibody, Growth arrest and DNA damage inducible alpha antibody, Growth arrest and DNA damage-inducible protein GADD45 alpha antibody

UniProt: P24522

Pathways: p53 Signaling, Cell Division Cycle