Integrin Alpha2b antibody (AA 639-887) (HRP)

Catalog No. ABIN7156459

This anti-Integrin Alpha2b antibody is a Rabbit Polyclonal antibody detecting Integrin Alpha2b in ELISA. Suitable for Human.

Quick Overview for Integrin Alpha2b antibody (AA 639-887) (HRP) (ABIN7156459)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin Alpha2b antibody is conjugated to HRP

Application: ELISA

Product Details anti-Integrin Alpha2b Antibody (HRP)

Binding Specificity: AA 639-887

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Integrin alpha-IIb protein (639-887AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: ITGA2B

Background:

Background: Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Aliases: antigen CD41 antibody, BDPLT16 antibody, BDPLT2 antibody, CD41 antibody, CD41B antibody, form 2 antibody, GP2B antibody, GPalpha IIb antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, Integrin alpha 2b antibody, Integrin alpha IIb antibody, Integrin alpha-IIb light chain antibody, Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) antibody, ITA2B_HUMAN antibody, Itga2b antibody, ITGAB antibody, platelet fibrinogen receptor, alpha subunit antibody, platelet glycoprotein IIb of IIb/IIIa complex antibody, Platelet membrane glycoprotein IIb antibody, platelet specific antigen BAK antibody, PPP1R93 antibody

UniProt: P08514

Pathways: Integrin Complex