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IFITM3 antibody (AA 1-57)

IFITM3 Reactivity: Human WB, ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7156687
  • Target See all IFITM3 Antibodies
    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
    Binding Specificity
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-57
    Reactivity
    • 38
    • 6
    • 5
    • 1
    • 1
    • 1
    Human
    Host
    • 29
    • 6
    • 3
    Rabbit
    Clonality
    • 32
    • 6
    Polyclonal
    Conjugate
    • 26
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFITM3 antibody is un-conjugated
    Application
    • 28
    • 18
    • 11
    • 10
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Interferon-induced transmembrane protein 3 protein (1-57AA)
    Isotype
    IgG
    Top Product
    Discover our top product IFITM3 Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
    Alternative Name
    IFITM3 (IFITM3 Products)
    Synonyms
    1110004C05Rik antibody, Cd225 antibody, Cdw217 antibody, DSPA2b antibody, Fgls antibody, IP15 antibody, mil-1 antibody, 1-8U antibody, rat8 antibody, Interferon-induced transmembrane protein 3 antibody, interferon induced transmembrane protein 3 antibody, ifm3 antibody, Ifitm3 antibody, IFITM3 antibody
    Background

    Background: IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.

    Aliases: 1 8U antibody, Fragilis antibody, IFITM3 antibody, IFM3_HUMAN antibody, Interferon induced transmembrane protein 3 (1 8U) antibody, Interferon Induced Transmembrane Protein 3 antibody, Interferon inducible antibody, Interferon inducible protein 1 8U antibody, Interferon Inducible Protein 15 antibody, Interferon Inducible Protein Homolog antibody, Interferon-induced transmembrane protein 3 antibody, Interferon-inducible protein 1-8U antibody, IP15 antibody

    UniProt
    Q01628
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