Kallikrein 6 antibody (AA 22-244)

Catalog No. ABIN7157217

The Rabbit Polyclonal anti-Kallikrein 6 antibody has been validated for WB, IHC, ELISA and IF. It is suitable to detect Kallikrein 6 in samples from Human.

Quick Overview for Kallikrein 6 antibody (AA 22-244) (ABIN7157217)

Target: Kallikrein 6 (KLK6)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Kallikrein 6 Antibody

Binding Specificity: AA 22-244

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Kallikrein-6 protein (22-244AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Kallikrein 6

Target: Kallikrein 6 (KLK6)

Alternative Name: KLK6

Background:

Background: Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.

Aliases: Bssp antibody, hK 6 antibody, hK6 antibody, Kallikrein 6 precursor antibody, Kallikrein related peptidase 6 antibody, Kallikrein-6 antibody, Kallikrein6 antibody, KLK 6 antibody, Klk 7 antibody, KLK 9 antibody, Klk29 antibody, Klk6 antibody, KLK6_HUMAN antibody, Klk7 antibody, KLK9 antibody, MGC9355 antibody, mGK 1 antibody, mGK1 antibody, MSP antibody, Neurosin antibody, Protease M antibody, Protease serine 18 antibody, Protease serine 9 antibody, PRSS 18 antibody, PRSS 9 antibody, PRSS18 antibody, PRSS9 antibody, Serine protease 18 antibody, Serine protease 9 antibody, SP 59 antibody, SP59 antibody, Tissue kallikrein antibody, TK antibody, Zyme antibody

UniProt: Q92876

Pathways: Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling