MRAP2 antibody (AA 66-205) (Biotin)

Catalog No. ABIN7159226

Product Details anti-MRAP2 Antibody (Biotin)

Target: MRAP2 (Melanocortin 2 Receptor Accessory Protein 2 (MRAP2))

Binding Specificity: AA 66-205

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRAP2 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Melanocortin-2 receptor accessory protein 2 protein (66-205AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MRAP2

Target: MRAP2 (Melanocortin 2 Receptor Accessory Protein 2 (MRAP2))

Alternative Name: MRAP2 (MRAP2 Products)

Synonyms: BB633055 antibody, RGD1309873 antibody, C9H6ORF117 antibody, C6orf117 antibody, RP11-51G5.2 antibody, bA51G5.2 antibody, melanocortin 2 receptor accessory protein 2 antibody, Mrap2 antibody, MRAP2 antibody

Background:

Background: Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP. May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R), however, additional evidences are required in vivo.

Aliases: MRAP2 antibody, C6orf117 antibody, Melanocortin-2 receptor accessory protein 2 antibody, MC2R accessory protein 2 antibody

UniProt: Q96G30