MBD3 antibody (AA 79-209) (Biotin)
Quick Overview for MBD3 antibody (AA 79-209) (Biotin) (ABIN7159614)
Target
See all MBD3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 79-209
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Methyl-CpG-binding domain protein 3 protein (79-209AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
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Alternative Name
- MBD3
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Background
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Background: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.
Aliases: AI181826 antibody, AU019209 antibody, MBD 3 antibody, Mbd3 antibody, MBD3: methyl CpG binding domain protein 3 antibody, MBD3_HUMAN antibody, Methyl CpG binding domain protein 3 antibody, Methyl CpG binding protein MBD3 antibody, Methyl-CpG-binding domain protein 3 antibody, Methyl-CpG-binding protein MBD3 antibody
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UniProt
- O95983
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Pathways
- Chromatin Binding
Target
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