MICA antibody (AA 24-307)

Catalog No. ABIN7159680

The Rabbit Polyclonal anti-MICA antibody has been validated for ELISA and IHC. It is suitable to detect MICA in samples from Human.

Quick Overview for MICA antibody (AA 24-307) (ABIN7159680)

Target: MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MICA antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-MICA Antibody

Binding Specificity: AA 24-307

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human MHC class I polypeptide-related sequence A protein (24-307AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MICA

Target: MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

Alternative Name: MICA

Background:

Background: Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.

Aliases: MHC class I chain-related protein A antibody, MHC class I chain-related protein B antibody, MHC class I polypeptide related sequence A antibody, MHC class I polypeptide related sequence B antibody, MHC class I polypeptide-related sequence A antibody, MIC-A antibody, micA antibody, MICA_HUMAN antibody, MICB antibody

UniProt: Q29983

Pathways: Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response