PTHLH antibody (AA 37-175)

Catalog No. ABIN7347993

Product Details anti-PTHLH Antibody

Target: PTHLH (Parathyroid Hormone-Like Hormone (PTHLH))

Binding Specificity: AA 37-175

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTHLH antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Parathyroid hormone-related protein (37-175AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PTHLH

Target: PTHLH (Parathyroid Hormone-Like Hormone (PTHLH))

Alternative Name: PTHLH (PTHLH Products)

Synonyms: BDE2 antibody, HHM antibody, PLP antibody, PTHR antibody, PTHRP antibody, PTHrP antibody, PTHLH antibody, pthlh antibody, pthrp antibody, si:ch211-286m4.5 antibody, PTH-like antibody, Pthrp antibody, PTHR1 antibody, parathyroid hormone like hormone antibody, parathyroid hormone-like hormone antibody, parathyroid hormone-like hormone a antibody, parathyroid hormone-like hormone L homeolog antibody, parathyroid hormone-like peptide antibody, parathyroid hormone 1 receptor antibody, PTHLH antibody, Pthlh antibody, pthlha antibody, pthlh.L antibody, PTH1R antibody

Background:

Background: Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath By similarity. Promotes colon cancer cell migration and invasion in an integrin alpha-6/beta-1-dependent manner through activation of Rac1.

Aliases: HHM antibody, MGC14611 antibody, Osteostatin antibody, Parathyroid hormon like hormone isoform 2 preproprotein antibody, Parathyroid hormone like hormone antibody, Parathyroid hormone like hormone isoform 1 preproprotein antibody, Parathyroid hormone like protein antibody, Parathyroid hormone like related protein antibody, Parathyroid hormone related protein antibody, Parathyroid hormone-like protein antibody, Parathyroid like protein antibody, PLP antibody, PTH related protein antibody, PTH-rP antibody, PTHLH antibody, PTHR antibody, PTHR_HUMAN antibody, PTHrP antibody, PTHrP[107-139] antibody

UniProt: P12272

Pathways: Hormone Activity, cAMP Metabolic Process