PLIN5 antibody (AA 305-453) (Biotin)

Catalog No. ABIN7365407

Product Details anti-PLIN5 Antibody (Biotin)

Target: PLIN5 (Perilipin 5 (PLIN5))

Binding Specificity: AA 305-453

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLIN5 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Perilipin-5 protein (305-453AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PLIN5

Target: PLIN5 (Perilipin 5 (PLIN5))

Alternative Name: PLIN5 (PLIN5 Products)

Synonyms: LSDA5 antibody, LSDP5 antibody, MLDP antibody, OXPAT antibody, 2310076L09Rik antibody, AI415325 antibody, AW109675 antibody, Lsdp5 antibody, PAT-1 antibody, perilipin 5 antibody, PLIN5 antibody, Plin5 antibody

Background:

Background: Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity).

Aliases: Lipid storage droplet protein 5 antibody, LSDA5 antibody, MLDP antibody, OXPAT antibody, Perilipin 5 antibody, Perilipin-5 antibody, PLIN5 antibody, PLIN5_HUMAN antibody

UniProt: Q00G26