MAS1 antibody (AA 285-325) (Biotin)

Catalog No. ABIN7346918

Product Details anti-MAS1 Antibody (Biotin)

Target: MAS1 (MAS1 Oncogene (MAS1))

Binding Specificity: AA 285-325

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAS1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Proto-oncogene Mas protein (285-325AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MAS1

Target: MAS1 (MAS1 Oncogene (MAS1))

Alternative Name: MAS1 (MAS1 Products)

Synonyms: MAS antibody, Mas-1 antibody, c-mas antibody, MAS1 antibody, MAS1 proto-oncogene, G protein-coupled receptor antibody, MAS1 oncogene antibody, proto-oncogene Mas antibody, MAS1 antibody, Mas1 antibody, LOC703105 antibody

Background:

Background: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.

Aliases: MAS antibody, MAS proto oncogene antibody, Mas-related G protein-coupled receptor A antibody, MAS_HUMAN antibody, Mas1 antibody, MAS1 oncogene antibody, MAS1 proto-oncogene, G protein-coupled receptor antibody, MGRA antibody, Proto-oncogene Mas antibody

UniProt: P04201

Pathways: ACE Inhibitor Pathway, Regulation of Carbohydrate Metabolic Process