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RASSF1 antibody (AA 23-145)

RASSF1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7167122
  • Target See all RASSF1 Antibodies
    RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
    Binding Specificity
    • 15
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-145
    Reactivity
    • 49
    • 29
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 44
    • 5
    • 1
    Rabbit
    Clonality
    • 46
    • 4
    Polyclonal
    Conjugate
    • 22
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RASSF1 antibody is un-conjugated
    Application
    • 28
    • 23
    • 13
    • 13
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Ras association domain-containing protein 1 protein (23-145AA)
    Isotype
    IgG
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  • Application Notes
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
    Alternative Name
    RASSF1 (RASSF1 Products)
    Synonyms
    RASSF1 antibody, zgc:92505 antibody, wu:fc17f02 antibody, zgc:112224 antibody, 123F2 antibody, NORE2A antibody, RASSF1A antibody, RDA32 antibody, REH3P21 antibody, AA536941 antibody, AU044980 antibody, Rassf1A antibody, Rassf1B antibody, Rassf1C antibody, NPR2-like, GATOR1 complex subunit antibody, Ras association (RalGDS/AF-6) domain family 1 antibody, Ras association domain family member 1 antibody, putative rassf1 antibody, Ras association domain family member 1 L homeolog antibody, Ras association (RalGDS/AF-6) domain family member 1 antibody, NPRL2 antibody, rassf1 antibody, RASSF1 antibody, Smp_157340 antibody, rassf1.L antibody, Rassf1 antibody
    Background

    Background: Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression. Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein. Isoform C has been shown not to perform these roles, no function has been identified for this isoform. Isoform A disrupts interactions among MDM2, DAXX and USP7, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage.

    Aliases: 123F2 antibody, Cardiac specific ras association domain family 1 protein antibody, cardiac-specific ras association domain family 1 protein, 123F2 antibody, NORE2A antibody, OTTHUMP00000195503 antibody, OTTHUMP00000195504 antibody, OTTHUMP00000195505 antibody, OTTHUMP00000195507 antibody, Pancreas specific ras association domain family 1 protein antibody, Ras association (RalGDS/AF 6) domain family member 1 antibody, Ras association domain-containing protein 1 antibody, RASF1_HUMAN antibody, Rassf1 antibody, RASSF1A antibody, RDA32 antibody, REH3P21 antibody, Tumor suppressor protein RDA32 antibody, WUGSC:H_LUCA12.5 antibody

    UniProt
    Q9NS23
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