ARHGAP1 antibody (AA 542-744)

Catalog No. ABIN7167919

Product Details anti-ARHGAP1 Antibody

Target: ARHGAP1 (rho GTPase Activating Protein 1 (ARHGAP1))

Binding Specificity: AA 542-744

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Rho GTPase-activating protein 10 protein (542-744AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ARHGAP1

Target: ARHGAP1 (rho GTPase Activating Protein 1 (ARHGAP1))

Alternative Name: ARHGAP1 (ARHGAP1 Products)

Synonyms: CDC42GAP antibody, RHOGAP antibody, RHOGAP1 antibody, p50rhoGAP antibody, B230365D05Rik antibody, C76222 antibody, Cdc42GAP antibody, RP23-12H6.2 antibody, fk03b12 antibody, fk61c06 antibody, wu:cegs2891 antibody, wu:fk03b12 antibody, wu:fk61c06 antibody, zgc:110361 antibody, arhgap1 antibody, arhgap1-a antibody, arhgap1-b antibody, cdc42gap antibody, p50rhogap antibody, rhogap antibody, rhogap1 antibody, rhogap68f antibody, Rho GTPase activating protein 1 antibody, Rho GTPase activating protein 1 S homeolog antibody, ARHGAP1 antibody, Arhgap1 antibody, arhgap1 antibody, arhgap1.S antibody

Background:

Background: GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).

Aliases: Arhgap10 antibody, Graf-related protein 2 antibody, GRAF2 antibody, GTPase regulator associated with focal adhesion kinase 2 antibody, PS GAP antibody, PSGAP antibody, RHG10_HUMAN antibody, Rho GTPase-activating protein 10 antibody, Rho-type GTPase-activating protein 10 antibody

UniProt: A1A4S6