AICDA antibody (AA 1-60) (FITC)
Quick Overview for AICDA antibody (AA 1-60) (FITC) (ABIN7169746)
Target
See all AICDA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-60
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Single-stranded DNA cytosine deaminase protein (1-60AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- AICDA (Activation-Induced Cytidine Deaminase (AICDA))
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Alternative Name
- AICDA
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Background
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Background: Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
Aliases: Activation induced cytidine deaminase antibody, Activation induced deaminase antibody, Activation-induced cytidine deaminase antibody, AICDA antibody, AICDA_HUMAN antibody, AID antibody, ARP 2 antibody, ARP2 antibody, CDA 2 antibody, CDA2 antibody, Cytidine aminohydrolase antibody, HIGM2 antibody, Integrated into Burkitt's lymphoma cell line Ramos antibody
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UniProt
- Q9GZX7
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Production of Molecular Mediator of Immune Response
Target
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