AICDA antibody (AA 1-60) (FITC)

Catalog No. ABIN7169746

The FITC-conjugated Rabbit Polyclonal anti-AICDA antibody (ABIN7169746) specifically detects AICDA. The antibody is reactive with Human samples.

Quick Overview for AICDA antibody (AA 1-60) (FITC) (ABIN7169746)

Target: AICDA (Activation-Induced Cytidine Deaminase (AICDA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AICDA antibody is conjugated to FITC

Application: Please inquire

Product Details anti-AICDA Antibody (FITC)

Binding Specificity: AA 1-60

Purpose: AICDA Antibody, FITC conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Single-stranded DNA cytosine deaminase protein (1-60AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AICDA

Target: AICDA (Activation-Induced Cytidine Deaminase (AICDA))

Alternative Name: AICDA

Background:

Background: Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.

Aliases: Activation induced cytidine deaminase antibody, Activation induced deaminase antibody, Activation-induced cytidine deaminase antibody, AICDA antibody, AICDA_HUMAN antibody, AID antibody, ARP 2 antibody, ARP2 antibody, CDA 2 antibody, CDA2 antibody, Cytidine aminohydrolase antibody, HIGM2 antibody, Integrated into Burkitt's lymphoma cell line Ramos antibody

UniProt: Q9GZX7

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Production of Molecular Mediator of Immune Response