SPOPL antibody (AA 1-120) (Biotin)

Catalog No. ABIN7170437

Product Details anti-SPOPL Antibody (Biotin)

Target: SPOPL (Speckle-Type POZ Protein-Like (SPOPL))

Binding Specificity: AA 1-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPOPL antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Speckle-type POZ protein-like protein (1-120AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SPOPL

Target: SPOPL (Speckle-Type POZ Protein-Like (SPOPL))

Alternative Name: SPOPL (SPOPL Products)

Synonyms: BTBD33 antibody, 4921517N04Rik antibody, AU014935 antibody, BB233739 antibody, E430033K04Rik antibody, RGD1305847 antibody, spopl antibody, wu:fi71d08 antibody, zgc:101524 antibody, speckle type BTB/POZ protein like antibody, speckle-type POZ protein-like antibody, protein roadkill-like antibody, speckle type POZ protein like L homeolog antibody, speckle-type POZ protein-like a antibody, SPOPL antibody, spopl antibody, LOC100371108 antibody, spopl.L antibody, Spopl antibody, spopla antibody

Background:

Background: Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP.

Aliases: SPOPL antibody, Speckle-type POZ protein-like antibody, HIB homolog 2 antibody, Roadkill homolog 2 antibody

UniProt: Q6IQ16